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Hormones and Inflammation

One of most effective ways to address inflammation is to balance and optimize hormones. Measuring hormone levels provides a clear indicator of underlying inflammation; if testosterone or growth hormone begin to drop, it indicates a problem. Elevated levels of some hormones, like cortisol and insulin, may also lead to increases in inflammation:

Hormone declines that result in increased inflammation:

  • Low Estrogen:
  • Increases IL-1, IL-6, TNF-alpha, Lipids
  • Low Testosterone:
  • Increases TNF- alpha, IL-6, CRP
  • TNF- alpha decreases Nitric Oxide production
  • Low Thyroid:
  • Correlated with elevated CRP and Metabolic Syndrome
  • Low DHEA:
  • Correlated with increased CRP, IL-6, NFk beta
  • Low Growth hormone correlated with:
  • Increased homocysteine
  • Increased adipose
  • Increased endothelial dysfunction and cardiac deaths


Hormone elevations resulting in increased inflammation:

  • High Cortisol:
  • Correlated with increased CRP, TNF-alpha
  • High Insulin:
  • Correlated with increased TNF-alpha, IL-6